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KMID : 1143120120020040280
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Asia Pacific Allergy
2012 Volume.2 No. 4 p.280 ~ p.282
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Biphasic anaphylaxis to gemifloxacin
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Yilmaz Insu
Dogan Serkan
Tutar Nuri
Kanbay Asiye
Buyukoglan Hakan
Demir Ramazan
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Abstract
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Anaphylaxis have been documented as adverse effects of ciprofloxacin, ofloxacin, norfloxacin, levofloxacin, and moxifloxacin. However resistant and biphasic anaphlylactic reactions to gemifloxacin have not been reported to date. Management of severe anaphylaxis in the elderly can be complicated by concurrent medications such as beta (β) adrenergic, alpha (α) adrenergic blockers and angiotensin-converting enzyme (ACE) inhibitors. We report here in the case of a 60-year-old male who was taking on ACE inhibitor, α and β blockers and experienced a severe, resistant and biphasic anaphlylactic reaction to gemifloxacin mesylate.
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KEYWORD
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Alpha blocker, Beta blocker, Biphasic anaphylaxis, Gemifloxacin, ACE inhibitor
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